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EgoCor - Simple Presentation of Estimated Exponential Semi-Variograms

User friendly interface based on the R package 'gstat' to fit exponential parametric models to empirical semi-variograms in order to model the spatial correlation structure of health data. Geo-located health outcomes of survey participants may be used to model spatial effects on health in an ego-centred approach. The package contains a range of functions to help explore the spatial structure of the data as well as visualize the fit of exponential models for various metaparameter combinations with respect to the number of lag intervals and maximal distance. Furthermore, the outcome of interest can be adjusted for covariates by fitting a linear regression in a preliminary step before the semi-variogram fitting process.

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4.78 score 3 stars 10 scripts 392 downloads

WSPsignal - Weibull Shape Parameter Tests for Signal Detection

Implementation of Bayesian and frequentist Weibull Shape Parameter (WSP) tests for signal detection in pharmacovigilance based on right-censored time-to-event data to flag associations between drugs and adverse events. The WSP test is based on the assumption of constant hazard reflected by a Weibull type distribution with shape parameters equal to one. Based on the shape parameter estimates (posterior distribution or point estimate), the WSP test method performs a hypothesis test on each shape parameter and combines them to a decision on the presence of a signal. Methods described in Sauzet and Cornelius (2022) <doi:10.3389/fphar.2022.889088>, Sauzet et al. (2024) <doi:10.1007/s40264-024-01460-2>, and Dyck and Sauzet (2025) <doi:10.48550/arXiv.2412.05463>.

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onetbbcpp

4.16 score 1 stars 1 scripts 261 downloads