Package: WSPsignal 1.0.0

WSPsignal: Weibull Shape Parameter Tests for Signal Detection

Implementation of Bayesian and frequentist Weibull Shape Parameter (WSP) tests for signal detection in pharmacovigilance based on right-censored time-to-event data to flag associations between drugs and adverse events. The WSP test is based on the assumption of constant hazard reflected by a Weibull type distribution with shape parameters equal to one. Based on the shape parameter estimates (posterior distribution or point estimate), the WSP test method performs a hypothesis test on each shape parameter and combines them to a decision on the presence of a signal. Methods described in Sauzet and Cornelius (2022) <doi:10.3389/fphar.2022.889088>, Sauzet et al. (2024) <doi:10.1007/s40264-024-01460-2>, and Dyck and Sauzet (2025) <doi:10.48550/arXiv.2412.05463>.

Authors:Julia Dyck [cre], Julia Dyck [aut], Odile Sauzet [aut]

WSPsignal_1.0.0.tar.gz
WSPsignal_1.0.0.zip(r-4.7-x86_64)WSPsignal_1.0.0.zip(r-4.7-arm64)WSPsignal_1.0.0.zip(r-4.6-x86_64)WSPsignal_1.0.0.zip(r-4.6-arm64)WSPsignal_1.0.0.zip(r-4.5-x86_64)
WSPsignal_1.0.0.tgz(r-4.6-x86_64)WSPsignal_1.0.0.tgz(r-4.6-arm64)WSPsignal_1.0.0.tgz(r-4.5-x86_64)WSPsignal_1.0.0.tgz(r-4.5-arm64)
WSPsignal_1.0.0.tar.gz(r-4.7-arm64)WSPsignal_1.0.0.tar.gz(r-4.7-x86_64)WSPsignal_1.0.0.tar.gz(r-4.6-arm64)WSPsignal_1.0.0.tar.gz(r-4.6-x86_64)
WSPsignal_1.0.0.tgz(r-4.6-emscripten)
manual.pdf |manual.html✨
DESCRIPTION
card.svg |card.png
WSPsignal/json (API)

# Install 'WSPsignal' in R:
install.packages('WSPsignal', repos = c('https://julia-dyck.r-universe.dev', 'https://cloud.r-project.org'))

Bug tracker:https://github.com/julia-dyck/wspsignal/issues

Uses libs:
  • onetbb– Parallelism library for C++
  • c++– GNU Standard C++ Library v3
Datasets:
  • muscu - Simulated musculoskeletal pain time-to-event dataset
  • muscu2 - Simulated musculoskeletal pain time-to-event dataset
  • tte - Test time-to-event dataset

On CRAN:

Conda:

onetbbcpp

4.16 score 1 stars 1 scripts 261 downloads 24 exports 73 dependencies

Last updated from:7901a622c1. Checks:15 OK. Indexed: yes.

TargetResultTimeFilesSyslog
linux-devel-arm64OK480
linux-devel-x86_64OK683
source / vignettesOK818
linux-release-arm64OK436
linux-release-x86_64OK358
macos-release-arm64OK411
macos-release-x86_64OK1549
macos-oldrel-arm64OK440
macos-oldrel-x86_64OK724
windows-devel-arm64OK697
windows-devel-x86_64OK537
windows-release-arm64OK702
windows-release-x86_64OK761
windows-oldrel-x86_64OK639
wasm-releaseOK377

Exports:bwsp_modelbwsp_testdpgweval.calc_perfeval.eff_sample_sizeseval.execution_timeseval.non_conv_caseseval.rank_auceval.roc_curvefwsp_modelfwsp_testhpgwplot_pgwppgwqpgwrpgwsim.datagen_ttesim.merge_resultssim.priors_templatesim.runsim.run_parallelsim.setup_sim_parsspgwtte2priordat

Dependencies:abindbackportsBHbitopscallrcaToolscheckmateclicodetoolscpp11descdigestdistributionaldplyrfarverfurrrfuturegenericsggplot2globalsgluegplotsgridExtragtablegtoolsHDIntervalinlineisobandKernSmoothlabelinglatticelifecyclelistenvloomagrittrMatrixmatrixStatsnumDerivotelparallellypillarpkgbuildpkgconfigposteriorprocessxpspurrrQuickJSRR6rbibutilsRColorBrewerRcppRcppEigenRcppParallelRdpackrlangROCRrstanrstantoolsS7scalesStanHeadersstringistringrsurvivaltensorAtibbletidyrtidyselectutf8vctrsviridisLitewithr